Thousands Of Women Get Pregnant Each Day, Some Are Estaticed

Thousands of women get pregnant each day, some are estaticed while others are not so much. Once a woman finds out she is pregnant it is up to her to decide if she wants to let the pregnancy continue or to terminate it. According to the Planned Parenthood website, â€Å"Abortions are very common. In fact, three out of ten women in the US have an abortion by the time they are forty- five years old.† While this is true, critics insist that some women do not know enough about abortions. According to them, it is important that a pregnant woman knows her different options. These options including continuing or terminating her pregnancy, sometimes the cost is the deciding factor. The costs of abortions vary depending on a few factors. One of those†¦show more content†¦This process lasts about five to ten minutes. Prices also continue to go up as a woman gets further into her pregnancy. According to the National Abortion Federation website, the cost of abortions range from three hundred and fifty dollars to well over one thousand dollars as the pregnancy continues. While the price goes up as pregnancy continues, a woman can only get an abortion up to the twenty-fourth week of pregnancy based on state laws. Throughout the United States of America different states have different laws on abortion. In some states a woman can receive an abortion up to being twenty-four weeks pregnant, while in other states she may only be able to receive an abortion up to being twenty weeks pregnant. Before states had the right to decide on their own laws pertaining to abortion, the federal government made abortions illegal. During the time that abortions were illegal in the US there was a huge push to legalize it. The people who pushed for abortions to be legal were worried about illegal abortions. Before 1973 and the court case of Roe versus Wade, abortions were illegal. Due to that fact, women were doing in-home abortions or going to someone, who was not qualified to do so, to get an abortion. These were very unsafe practices. Sometimes these â€Å"abortions† were unsuccessful and the child would still be born but with birth defects. Or if the abortion was successful in

The Founding Brothers By Joseph J. Ellis - 1253 Words

In the book the Founding Brothers, Joseph J. Ellis, the author puts the key players of post – revolution America on BLAST! His slam book, closely mirrors the political turmoil of today. It is marred by a war of words between candidates, personal attacks, media bias, party politics and long standing feuds. Ellis’ factual account of the historical crisis explores challenges each of these ordinary men, our founding fathers faced as they come together to established order and declare their independence from Britain in a brave new world. Ellis an excellent story teller is one of the leading scholar of American history. He was a college professor and previously taught at the Honors College at the University of Massachusetts. He has written†¦show more content†¦And that these men were wise intellectual whose compromises sometimes saved the day and preserved the laws of the nation for the people. Ellis skips the order of historical events as they happened and begins with the infamous duel of 1804, between Alexander Hamilton and Aaron Burr. He purposely skips George Washington’s election as the first President of the United States in 1789 and focuses on a detail analysis of the jealousy between these two ambitious founding fathers. Their unavoidable deadly confrontation that ends in a duel near Weehawken, New Jersey. The duel that leaves Hamilton mortally wounded and Burr charged with his murder. Ellis convinces us to believe that honor and respect was the motive here because Hamilton had written in his earlier memoirs that he did not plan to shoot Burr and hoped that he would somehow miss him. __________________________________________________________________________________ Hamilton the self-taught college dropout and the illegitimate son of a Scottish alcoholic disliked Burr the academic intellectual from New Jersey. Both men served their country during the Revolutionary War and became politically active. Hamilton, a member of the Federalist Party was pro-central government and believed in the preservation of the Union at all cost. He was a protà ©gà © of George Washington and held several prestigious positions within his administration. He wasShow MoreRelatedFounding Brothers By Joseph J. Ellis1479 Words   |  6 Pages In the book â€Å"Founding Brothers† by Joseph J. Ellis, he explores the challenges faced by the Founding Fathers in a series of 6 defining events as they formed a new government for the U.S. after the revolution. Focusing on the more important figures from the revolutionary era, who he calls â€Å"Founding Brothers†, a slight change from the original â€Å"Founding Fathers†. They are as follows: George Washington, John and Abigale Adams, James Madison, Thomas Jefferson, Arron Burr, Alexander Hamilton, and BenjaminRead More Joseph J. Ellis Founding Brothers : The Revoluntary Generation654 Words   |  3 PagesJoseph J. Ellis Founding Brothers : The Revoluntary Generation   Ã‚  Ã‚  Ã‚  Ã‚  The compelling and infectious novel of Founding Brothers; The Revolutionary Generation written by Joseph J. Ellis combines our founding fathers weakness’ and strongest abilities in just six chapters. His six chapters tell the stories of: The duel between Alexander Hamilton and Aaron Burr. This entertaining chapter describes how duels were undertaken and played out in that time, and helps the reader understand both mens motivesRead MoreFounding Brothers by Joseph J. Ellis Essay1411 Words   |  6 PagesFounding Brothers Essay The founding fathers, or as the book calls them the founding brothers, are an assorted group of men from wildly different backgrounds. In political terms, they were divided. Yet, they came to together to help shape this country into the place it is today. Now on their journey towards the making of this country they did encounter some trouble. They encountered heated debates among themselves though for getting through these debates they show just why they deserve to be calledRead MoreSummary Of Founding Brothers : The Revolutionary Generation By Joseph J. Ellis1377 Words   |  6 Pages2015 Summer Book Review Founding Brothers: The Revolutionary Generation by Joseph J. Ellis Publisher: Alfred A. Knopf Joseph J. Ellis work concentrates on crucial events after the Revolutionary war in the young nation of America. The writer unbiasedly analyzes vital moments in the lives of the Founding Fathers and how relationships between them influenced and were influenced by the unstable era in which they happened to live in. Through the six chapters and preface, Ellis examines the key revolutionaryRead MoreRespectability: Politics in Early America in Founding Brothers by Joseph J. Ellis1507 Words   |  7 PagesIn Founding Brothers, Joseph J. Ellis discusses how the relationships of the founding fathers shaped the United States, looking not only at what happened historically but the myths that have prevailed in modern times. I have few issues with this book one of which is that the narrative often jumps from one time and place to another, and while it provides the relevant information and keeps the reader’s attention, it can be hard to follow at times. In addition there are times were he explains the sameRead Morefounding fathers book report873 Words   |  4 PagesJoseph J. Ellis is a well-known historian. He earned his Bachelor’s degree from the college of William and Mary, and his masters and Ph.D. at the University of Yale. Ellis is currently a full time professor of the Commonwealth at the University of Massachusetts at Amherst. In addition to Founding Brothers: The Revolutionary Generation Ellis has written many books and editorials. His books include; The New England Mind in Transition: Samuel Johnson of Connecticut (Yale University Press, 1983)Read MoreFounding Brothers : The Revolutionary Generation Essay1261 Words   |  6 PagesJoseph J. Ellis, American historian and novelist has written many awards winning novels. One of his most recognized, â€Å"American Sphinx†, winner many prestigious awards such as the National Book Award for Non-Fiction in 1997, and the Ambassador Book Award for Biography in 1998. His Pulitzer Prize winning novel, â€Å"Founding Brothers: The Revolutionary Generation†, talks about the founding fathers’ interactions with each other in the decades that followed the Constitutional Convention of 1787. DuringRead MoreFounding Brothers Book Review Essay627 Words   |  3 PagesEllis, Joseph J.  Founding Brothers: The Revolutionary Generation.  New York: Alfred A. Knopf, 2000. Print. The book being critiqued in the following review is Founding Brothers by Joseph Ellis. Ellis’ goal in writing this book was to define the political events and achievements that gained historical significance because they framed the successive history of the United States. Ellis wrote on this specific topic because he felt the need to argue the fact that the American Revolution and the greatnessRead MoreThe American Revolution : A Historiographical Introduction846 Words   |  4 PagesRevolution: A Historiographical Introduction,† provided by The British Library I would choose to use a book titled â€Å"Revolutionary Characters: What Made The Founders Different,† written by Gordon S. Wood, and a book titled â€Å"Founding Brothers: The Revolutionary Generation,† written by Joseph J Ellis as reference. The article â€Å"The American Revolution: A Historiographical Introduction,† provided by The British Library, goes over how the American Revolution’s history has changed throughout the yearsRead MoreThe Revolutionary Generation, By Joseph J. Ellis1730 Words   |  7 PagesJoseph J. Ellis, the author of Founding Brothers: The Revolutionary Generation, is an American author and historian. Born July 18, 1943 in Washington, D.C., Ellis would grow up to be one of the best, well-known scholars of America. He began his college education at Yale University, then at the College of William Mary. Ellis works include Founding Brothers: The Revolutionary Generation, American Sphinx, and His Excellency: George Washington. His books have brought his name into one of remembrance

Pervasis Case Study Free Essays

Pervasis Receives Orphan Drug Designation in Europe for Vascugel ® to Prevent Arteriovenous Access Failure in Patients Undergoing Hemodialysis Cell-Based Therapy Aims to Regulate the Body’s Healing Response, Promoting Vascular Repair, Reducing the Need for Repeat Surgical Procedures and Improving Patient Outcomes Cambridge, Mass. , March 1, 2011 — Pervasis Therapeutics, Inc. announced today that the European Commission (EC) has granted Orphan Drug Designation for Vascugel ® for the prevention of hemodialysis vascular access failure in patients with end stage renal disease (ESRD). We will write a custom essay sample on Pervasis Case Study or any similar topic only for you Order Now The designation follows a positive opinion from The Committee for Orphan Medicinal Products (COMP) within the European Medicines Agency (EMA) earlier this year. Vascugel is a novel endothelial cell-based therapy that aims to regulate the body’s healing response following surgical interventions to create vascular access which are necessary for ESRD patients undergoing hemodialysis. By promoting and enhancing vascular repair, Vascugel reduces the need for repeat surgical interventions and improves overall patient outcomes. ESRD is an advanced and irreversible condition treated mainly by hemodialysis or kidney transplantation. It is estimated that more than 250,000 ESRD patients in the EU receive hemodialysis, a blood purification therapy designed to replace critical kidney functions – such as filtering waste. Orphan Drug Designation by the EC provides regulatory and financial incentives for companies to develop and market therapies that treat a life-threatening or chronically debilitating condition affecting no more than five in 10,000 persons in the European Union (EU). In addition to a 10year period of marketing exclusivity in the EU after product approval, Orphan Drug Designation provides companies with scientific advice and regulatory assistance from the EMA during the product development phase, direct access to centralized marketing authorization, as well as reductions in certain fees. We are committed to bringing Vascugel to patients with end stage renal disease who currently must endure serious complications and repeat surgical procedures so they can continue to receive life-saving hemodialysis treatment,† Frederic Chereau, president and chief executive officer of Pervasis. â€Å"Receiving Orphan Drug Designation in the EU is an important step, as it will help to advance the development process, and enhance our ability to deliver our novel cellbased therapeutic approach to address this significant unmet medical need. Vascugel has demonstrated proof of concept in two Phase 2 clinical trials involving patients with ESRD who require a permanent arteriovenous (AV) access in order to undergo hemodialysis. In these trials, Vascugel exhibited an excellent safety profile, and encouraging efficacy trends were observed, including improved duration of patency (or unimpeded blood flow) and a delay in time to first intervention as compared to placebo. In 2009, Pervasis received Orphan Drug Designation from the U. S. Food and Drug Administration (FDA) for Vascugel in patients with ESRD. Pervasis announced last month that the FDA had granted Fast Track review status for Vascugel. Last year, Pervasis reached an agreement with the FDA for a Phase 3 clinical trial of Vascugel under the Agency’s Special Protocol Assessment (SPA) procedure, whereby FDA formalized its agreement that the design of the Phase 3 trial was acceptable to support a regulatory submission seeking new drug approval. Failure of Hemodialysis Access Points Leads to Poor Outcomes During hemodialysis, blood is removed from the body, filtered through a dialyzer, or artificial kidney, and then returned to the body. Patients must undergo a surgical intervention to create a vascular access that enables blood to flow from the body to the dialyzer and back to the body. AV fistulae (created by directly joining an artery and vein) and AV grafts (created using a synthetic tube to join an artery and vein) are the two primary types of hemodialysis access. Due to an inflammatory cascade triggered by surgical intervention, the vascular access often has difficulty healing, and quickly become unusable or clot rapidly, prompting the need for additional, recurring surgeries to create a new access which can lead to multiple complications. Up to 60 percent of all arteriovenous (AV) grafts require re-intervention after one year. 1, 2 AV access failure is the most common reason for hospitalization among hemodialysis patients and can lead to anemia, infection, weight loss, jaundice, prolonged bleeding, and other serious complications. Vascugel ® – Combating Inflammation and Promoting Healing Pervasis’ novel approach to cell therapy uses adult-differentiated allogeneic endothelial cells (donor endothelial cells with a highly targeted biologic function) embedded in a polymer matrix to enhance the body’s natural healing response. The endothelium is the thin layer of cells that lines the interior surface of blood vessels in th e body. Endothelial cells are critical to tissue repair and health, and have a well-understood role in regulating many of the body’s healing processes, including those associated with vascular repair. Vascugel, which utilizes Pervasis’ patented endothelial cell-based platform, is placed on the outside of the blood vessel at the AV access site during the surgical intervention to create the access. The endothelial formulation in Vascugel secrete several factors that combat inflammation and promote proper vascular healing, reducing thrombosis (or clotting) and the formation of intimal hyperplasia, or a thickening of the blood vessel wall in response to injury. After approximately four to eight weeks, Vascugel is safely resorbed by the body. Pervasis’ other areas of clinical investigation include improving outcomes in patients with peripheral artery disease (PAD) following surgical procedures such as percutaneous transluminal angioplasties (PTAs) with stenting, the failures of which result in serious complications and a significant increase in medical costs. Earlier this year, Pervasis announced it has also embarked on an oncology development program using its proprietary endothelial cellbased platform to prevent solid tumor growth, cancer recurrence and metastatic disease. About Pervasis Dixon et al. DAC Study Group. Effect of dipyridamole plus aspirin on hemodialysis graft patency. N Engl J Med. 2009; 360: 2191-2201. 2 Hayashi et al. Vascular access for hemodialysis. Nat Clin Pract Nephrol 2006; 2: 504-513 3 Castner D. Recommendations for tracking arteriovenous access complications using a charting-by-exception model. Anna Journal, 1998; 25(4): 393-396. 1 Pervasis Inc. is a clinical stage company that is developing groundbreaking endothelial cellbased therapies designed to regulate the body’s natural healing and repair processes in various critical therapeutic areas. The company has initially focused on developing therapies to improve the outcomes of common vascular interventions, such as arteriovenous access, angioplasties, stent placements, and peripheral and coronary bypass grafts – the failure of which result in serious complications and a significant increase in medical costs. The company’s lead program, Vascugel ®, has demonstrated proof of concept and safety in two Phase 2 clinical trials. Pervasis is also applying its endothelial cell-based platform technology to develop an oncology therapy focused on preventing solid tumor growth, cancer recurrence and metastatic disease, as well as products for inflammatory disease and orthopedic injury. Pervasis is a privately held company with funding from Flagship Ventures, Polaris Venture Partners, Highland Capital Partners and the Richter Family Fund. For more information, please visit www. pervasistx. com. This news release contains certain forward-looking statements that involve risks and uncertainties. Such statements are only predictions and the company’s actual results may differ materially from those anticipated in these forward-looking statements. Factors that may cause such differences include the timing of clinical trials, the risk that products that appeared promising in early research and clinical trials do not demonstrate safety or efficacy in clinical trials and the risk that the company will not obtain approval to market its products. Company Contact: Margaret O’Toole Pervasis Therapeutics, Inc. 617-871-1201 motoole@pervasistx. com Media Contact: Liz Falcone Feinstein Kean Healthcare 617-256-6622 liz. falcone@fkhealth. com How to cite Pervasis Case Study, Free Case study samples